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Polyethylene glycol PEG is a polymer prepared by stepwise addition reaction of ethylene oxide with water or ethylene glycol as raw material. It is a white paraffin-like flake or powder solid, odorless or with weak odor. The structure of PEG is simple, non-toxic, non-irritating, has good water solubility, and has good compatibility with many organic components.
Physical and chemical properties of polyethylene glycol PEG
Polyethylene glycol PEG is a colorless or slightly yellow liquid or semi-solid easily soluble in water, with low toxicity, tasteless, odorless, non-volatile, non-burning characteristics, liquid at room temperature. The main characteristic of PEG is its oxidation chemical property on the molecular chain, which makes it soluble, stable and biocompatible.
Polyethylene glycol PEG is soluble in most solvents, including water, methanol, ethanol, ether, dichloromethane, etc. At the same time, PEG also has certain surface activity, which can cooperate with drugs or biological macromolecules to improve the water solubility and bioavailability of drugs.
Three application safety issues of polyethylene glycol PEG
The toxicity of polyethylene glycol PEG is low and does not cause obvious harm to the human body, but high concentrations of PEG can induce allergic reactions such as urticaria and skin allergy, and there is a risk of sensitization for some people.
Polyethylene glycol PEG is a flammable substance, the compound will release toxic gases and harmful substances when burning, and should be used to avoid Mars and high temperatures.
Polyethylene glycol PEG will react with other drugs or chemicals, and should be avoided for substances that cannot be dissolved in the compound.
In short, polyethylene glycol PEG is a compound with multiple functions, and is currently widely used in cosmetics, medicine, food, industry and other fields. Although polyethylene glycol PEG has reliable physical and chemical properties and a wide range of applications, it is still necessary to pay attention to some safety issues described above when using.