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Polyethylene glycol (PEG) is a polymer prepared by step-by-step addition reaction of ethylene oxide with water or ethylene glycol as raw materials. It is a white waxy solid in flake or powder form with no odor or a faint odor. It is non-toxic and non-irritating, and has good water solubility, as well as good compatibility with many organic components.
Physicochemical Properties of Polyethylene Glycol (PEG)
Polyethylene glycol (PEG) is a colorless or slightly yellow liquid or semisolid that is easily soluble in water. It has low toxicity, no taste, no odor, non-volatile, and non-flammable characteristics, and is liquid at room temperature. The main characteristic of PEG is its oxygen-containing chemical properties on its molecular chain, which give it solubility, stability, and biocompatibility.
PEG is soluble in most solvents, including water, methanol, ethanol, ether, dichloromethane, etc. At the same time, PEG also has a certain surface activity, which can coordinate with drugs or biomolecules to improve the water solubility and bioavailability of drugs.
PEG is non-toxic and non-irritating, with good water solubility and good compatibility with many organic components. They have excellent lubricity, moisturizing, dispersing, adhesive, antistatic, and softening properties.
Three Key Safety Applications of Polyethylene Glycol (PEG)
1. PEG has a lower toxicity and does not cause obvious harm to the human body, but high concentrations of PEG can induce symptoms such as hives and skin allergies, and there is a risk of sensitization to certain populations.
2. PEG is a flammable substance, and the compound releases toxic gases and harmful substances when burned. It should be avoided in the presence of sparks and high temperatures when used.
3. PEG PEG may react chemically with other drugs or chemicals, and substances that cannot be dissolved in the compound should be avoided.